HitPredict

Interactor 1: KI3L1 (P43629)
Killer cell immunoglobulin-like receptor 3DL1 (CD158 antigen-like family member E) (HLA-BW4-specific inhibitory NK cell receptor) (Natural killer-associated transcript 3) (NKAT-3) (p70 natural killer cell receptor clones CL-2/CL-11) (p70 NK receptor CL-2/CL-11) (CD antigen CD158e)
Gene: KIR3DL1

Interactor 2: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15187115
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0060090 - molecular adaptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 593
+	Hs
		665821 KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		601501 FGFR2_HUMAN (2-391): 9.5e-60: 210: 13.89		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Mm
		719307 LRB4A_MOUSE (1-233): 4.98e-58: 195: 27.85		PTN11_MOUSE (1-593): 0: 580: 99.49
+	Mm
		719316 Q8K4V6_MOUSE (23-425): 1.7e-45: 169: 25.48		PTN11_MOUSE (1-593): 0: 580: 99.49
+	Hs
		986023 KI2L4_HUMAN (1-230): 6.8e-46: 165: 53.48		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		601466 FGFR2_HUMAN (2-391): 9.5e-60: 210: 13.89		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		798184 KI2L3_HUMAN (1-241): 1.92e-42: 154: 38.82		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		665922 LIRB1_HUMAN (1-427): 1.83e-57: 202: 29.13		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Mm
		719293 LIRB3_MOUSE (21-424): 3.22e-39: 152: 23.98		PTN11_MOUSE (1-593): 0: 580: 99.49
+	Hs
		798139 KI2L1_HUMAN (1-233): 1.07e-40: 150: 39.17		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		252776 LIRB3_HUMAN (1-341): 7.95e-57: 199: 31.23		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		665916 LIRB2_HUMAN (1-444): 6.31e-57: 199: 29.94		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Mm
		665991 LRB4A_MOUSE (1-233): 4.98e-58: 195: 27.85		PTN6_MOUSE (6-583): 0: 530: 55.94
+	Hs
		665921 LIRB4_HUMAN (1-237): 4.06e-52: 183: 32.92		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		665820 KI2L3_HUMAN (1-241): 1.92e-42: 154: 38.82		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Mm
		665982 LIRB3_MOUSE (21-424): 3.22e-39: 152: 23.98		PTN6_MOUSE (6-583): 0: 530: 55.94
+	Hs
		665819 KI2L1_HUMAN (1-233): 1.07e-40: 150: 39.17		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		616999 LIRB4_HUMAN (1-237): 4.06e-52: 183: 32.92		PTPRD_HUMAN (39-522): 2.1e-115: 379: 26.76
+	Hs
		616953 KI2L1_HUMAN (1-233): 1.07e-40: 150: 39.17		PTPRD_HUMAN (39-522): 2.1e-115: 379: 26.76
+	Hs
		1069932 LRIG3_HUMAN (25-387): 3.7e-55: 199: 14.40		PTPRK_HUMAN (36-524): 5.17e-72: 254: 18.94