HitPredict

Interactor 1: KI3L1 (P43629)
Killer cell immunoglobulin-like receptor 3DL1 (CD158 antigen-like family member E) (HLA-BW4-specific inhibitory NK cell receptor) (Natural killer-associated transcript 3) (NKAT-3) (p70 natural killer cell receptor clones CL-2/CL-11) (p70 NK receptor CL-2/CL-11) (CD antigen CD158e)
Gene: KIR3DL1

Interactor 2: KI3S1 (Q14943)
Killer cell immunoglobulin-like receptor 3DS1 (Natural killer-associated transcript 10) (NKAT-10)
Gene: KIR3DS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	ig~ig
Common GO terms	GO:0005886 - plasma membrane GO:0006955 - immune response
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 382
+	Hs
		47501 A0A8I5QEB2_HUMAN (1-427): 3.73e-100: 306: 72.83		KI2S5_HUMAN (1-241): 3.77e-43: 154: 36.08
+	Hs
		1235887 LIRA3_HUMAN (1-342): 1.66e-71: 234: 35.06		LIRB1_HUMAN (21-344): 4.61e-57: 198: 35.53
+	Hs
		1235888 LIRA3_HUMAN (1-342): 1.66e-71: 234: 35.06		U5XH19_HUMAN (1-341): 2.78e-58: 198: 31.71
+	Hs
		252771 LIRA3_HUMAN (1-342): 1.66e-71: 234: 35.06		LIRA1_HUMAN (1-341): 6.68e-57: 195: 32.95
+	Hs
		1232784 LIRA3_HUMAN (1-342): 1.66e-71: 234: 35.06		LIRB2_HUMAN (1-341): 2.59e-55: 193: 35.53
+	Hs
		798163 KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00		KI2L2_HUMAN (218-346): 5.9e-14: 74: 34.85
+	Hs
		798136 KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00		KI2L1_HUMAN (218-346): 2.66e-13: 72.1: 33.33
+	Hs
		507854 FGFR2_HUMAN (2-391): 9.5e-60: 210: 13.89		FGFR1_HUMAN (3-369): 3.89e-60: 209: 14.18
+	Hs
		601455 FGFR2_HUMAN (2-391): 9.5e-60: 210: 13.89		FGFR2_HUMAN (2-379): 8.05e-60: 208: 13.78
+	Hs
		798230 KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00		KI2S2_HUMAN (218-341): 5.44e-10: 61.7: 34.65
+	Hs
		1161634 LIRA6_HUMAN (1-442): 4.2e-60: 205: 26.75		U5XH19_HUMAN (1-341): 2.78e-58: 198: 31.71
+	Hs
		252781 LIRA6_HUMAN (1-442): 4.2e-60: 205: 26.75		LIRB3_HUMAN (1-341): 4.19e-57: 198: 30.66
+	Hs
		87574 C9JWL8_HUMAN (1-341): 1.37e-57: 202: 32.09		U5XH19_HUMAN (1-341): 2.78e-58: 198: 31.71
+	Hs
		798168 KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66		KI2L2_HUMAN (218-346): 5.9e-14: 74: 34.85
+	Hs
		1232785 LIRB2_HUMAN (1-444): 6.31e-57: 199: 29.94		LIRB4_HUMAN (21-137): 3.84e-21: 96.3: 34.43
+	Ce
		103933 SAX3_CAEEL (20-424): 1.78e-58: 209: 11.71		SAX3_CAEEL (27-214): 1.03e-16: 84.1: 10.89