HitPredict

Interactor 1: KI3L2 (P43630)
Killer cell immunoglobulin-like receptor 3DL2 (CD158 antigen-like family member K) (Natural killer-associated transcript 4) (NKAT-4) (p70 natural killer cell receptor clone CL-5) (p70 NK receptor CL-5) (CD antigen CD158k)
Gene: KIR3DL2

Interactor 2: Q5S3G3 (Q5S3G3)
HLA class I histocompatibility antigen A alpha chain (MHC class I antigen)
Gene: HLA-A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	24018270
Identification Methods	surface plasmon resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 455 Hs			1 365
+	Hs
		382341 KI3L2_HUMAN (1-455): 5e-121: 362: 100.00		HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08
+	Hs
		47499 A0A8I5QEB2_HUMAN (1-427): 1.07e-105: 321: 74.94		HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08
+	Hs
		1060406 KI3S1_HUMAN (1-369): 7.84e-102: 310: 84.28		Q95J06_HUMAN (1-365): 0: 511: 92.06
+	Hs
		382420 KI3S1_HUMAN (1-369): 7.84e-102: 310: 84.28		HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08
+	Hs
		354353 KI3L2_HUMAN (1-455): 5e-121: 362: 100.00		HLAB_HUMAN (1-362): 3.65e-158: 449: 85.91
+	Hs
		354352 KI3L1_HUMAN (1-444): 1.03e-119: 358: 85.59		HLAB_HUMAN (1-362): 3.65e-158: 449: 85.91
+	Hs
		1060403 KI3S1_HUMAN (1-369): 7.84e-102: 310: 84.28		Q5SUL5_HUMAN (1-365): 3.17e-176: 495: 96.99
+	Hs
		570311 KI3L1_HUMAN (1-444): 1.03e-119: 358: 85.59		HLAG_HUMAN (1-338): 1.08e-151: 432: 82.25
+	Hs
		47498 A0A8I5QEB2_HUMAN (1-427): 1.07e-105: 321: 74.94		HLAB_HUMAN (1-362): 3.65e-158: 449: 85.91
+	Hs
		673945 KI3L2_HUMAN (1-455): 5e-121: 362: 100.00		HLAF_HUMAN (4-348): 1.95e-141: 406: 80.58
+	Hs
		1060402 KI3S1_HUMAN (1-369): 7.84e-102: 310: 84.28		Q546I9_HUMAN (1-362): 4.69e-161: 457: 84.53
+	Hs
		673944 KI3L1_HUMAN (1-444): 1.03e-119: 358: 85.59		HLAF_HUMAN (4-348): 1.95e-141: 406: 80.58
+	Hs
		354449 KI3S1_HUMAN (1-369): 7.84e-102: 310: 84.28		HLAB_HUMAN (1-362): 3.65e-158: 449: 85.91
+	Hs
		488296 KI3L3_HUMAN (1-427): 4.19e-106: 322: 75.18		HLAC_HUMAN (1-364): 1.31e-151: 433: 80.82
+	Hs
		47500 A0A8I5QEB2_HUMAN (1-427): 1.07e-105: 321: 74.94		HLAC_HUMAN (1-364): 1.31e-151: 433: 80.82
+	Hs
		488221 KI3S1_HUMAN (1-369): 7.84e-102: 310: 84.28		HLAC_HUMAN (1-364): 1.31e-151: 433: 80.82
+	Hs
		382280 FGFR1_HUMAN (5-455): 2.76e-65: 226: 16.21		HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08
+	Hs
		382306 FGFR2_HUMAN (2-455): 2.09e-65: 226: 14.89		HLAA_HUMAN (1-365): 6.07e-179: 502: 98.08
+	Hs
		673954 KI3S1_HUMAN (1-369): 7.84e-102: 310: 84.28		HLAF_HUMAN (4-348): 1.95e-141: 406: 80.58
+	Hs
		533162 LRIG1_HUMAN (7-450): 4e-61: 217: 12.74		HLAE_HUMAN (20-357): 9.86e-145: 415: 78.99