HitPredict

Interactor 1: KI2S2 (P43631)
Killer cell immunoglobulin-like receptor 2DS2 (CD158 antigen-like family member J) (NK receptor 183 ActI) (Natural killer-associated transcript 5) (NKAT-5) (p58 natural killer cell receptor clone CL-49) (p58 NK receptor CL-49) (CD antigen CD158j)
Gene: KIR2DS2

Interactor 2: KI2S1 (Q14954)
Killer cell immunoglobulin-like receptor 2DS1 (CD158 antigen-like family member H) (MHC class I NK cell receptor Eb6 ActI) (CD antigen CD158h)
Gene: KIR2DS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.712

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	ig~ig
Common GO terms	GO:0004888 - transmembrane signaling receptor activity GO:0005886 - plasma membrane GO:0006955 - immune response GO:0016020 - membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 304
+	Hs
		798257 KI2S2_HUMAN (1-304): 9.17e-119: 345: 100.00		KI2S2_HUMAN (1-304): 8.51e-111: 324: 93.75
+	Hs
		798259 KI2S2_HUMAN (1-304): 9.17e-119: 345: 100.00		KI2S5_HUMAN (1-304): 1.13e-107: 317: 92.11
+	Hs
		798258 KI2S2_HUMAN (1-304): 9.17e-119: 345: 100.00		KI2S3_HUMAN (1-304): 3.88e-107: 315: 91.45
+	Hs
		1060411 KI2S5_HUMAN (1-304): 2.21e-115: 336: 91.78		KI2S3_HUMAN (1-304): 3.88e-107: 315: 91.45
+	Hs
		798164 KI2S2_HUMAN (1-304): 9.17e-119: 345: 100.00		KI2L2_HUMAN (1-303): 9.5e-100: 298: 90.43
+	Hs
		798169 KI2S3_HUMAN (1-304): 7.03e-115: 335: 91.78		KI2L2_HUMAN (1-303): 9.5e-100: 298: 90.43
+	Hs
		798142 KI2S3_HUMAN (1-304): 7.03e-115: 335: 91.78		KI2L1_HUMAN (1-303): 8.01e-99: 295: 93.73
+	Hs
		798180 KI2L3_HUMAN (1-304): 9.06e-110: 323: 95.72		KI2L3_HUMAN (1-304): 5.29e-102: 304: 90.79
+	Hs
		798265 KI2S2_HUMAN (1-304): 9.17e-119: 345: 100.00		KI2LA_HUMAN (1-304): 2.71e-88: 270: 65.13
+	Hs
		798135 KI2L2_HUMAN (1-303): 8.23e-107: 316: 95.71		KI2L1_HUMAN (1-303): 8.01e-99: 295: 93.73
+	Hs
		798230 KI2S2_HUMAN (1-304): 9.17e-119: 345: 100.00		KI3L1_HUMAN (1-246): 3.84e-54: 184: 38.15
+	Hs
		47501 KI2S5_HUMAN (1-304): 2.21e-115: 336: 91.78		A0A8I5QEB2_HUMAN (1-246): 9.17e-56: 187: 40.96
+	Hs
		798163 KI2L2_HUMAN (1-303): 8.23e-107: 316: 95.71		KI3L1_HUMAN (1-246): 3.84e-54: 184: 38.15
+	Hs
		798168 KI2L2_HUMAN (1-303): 8.23e-107: 316: 95.71		KI3S1_HUMAN (1-246): 5.13e-53: 179: 37.75