HitPredict

Interactor 1: LPAR6 (P43657)
Lysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor)
Gene: LPAR6

Interactor 2: AT8B2 (P98198)
Phospholipid-transporting ATPase ID (EC 7.6.2.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2)
Gene: ATP8B2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 1209
+	Hs
		895607 CXCR4_HUMAN (7-311): 7.44e-68: 218: 27.60		AT8B2_HUMAN (1-1209): 0: 1173: 100.00
+	Hs
		254325 P2RY2_HUMAN (9-297): 1.06e-83: 259: 33.56		ATP9A_HUMAN (3-1118): 0: 746: 27.99
+	Hs
		782425 P2RY2_HUMAN (9-297): 1.06e-83: 259: 33.56		AT2B3_HUMAN (5-1199): 0: 744: 15.02
+	Hs
		619229 GPR17_HUMAN (6-302): 2.26e-84: 261: 32.55		AT2B4_HUMAN (11-1207): 0: 721: 15.27
+	Hs
		619207 P2RY2_HUMAN (9-297): 1.06e-83: 259: 33.56		AT2B4_HUMAN (11-1207): 0: 721: 15.27
+	Hs
		674851 AGTR1_HUMAN (5-340): 4.07e-72: 229: 25.22		AT2B3_HUMAN (5-1199): 0: 744: 15.02
+	Hs
		895636 CXCR4_HUMAN (7-311): 7.44e-68: 218: 27.60		AT2B3_HUMAN (5-1199): 0: 744: 15.02
+	Hs
		208456 OX2R_HUMAN (8-344): 2.03e-66: 217: 17.73		AT2B3_HUMAN (5-1199): 0: 744: 15.02
+	Hs
		781059 OPRX_HUMAN (5-323): 4.51e-67: 217: 22.98		AT2B3_HUMAN (5-1199): 0: 744: 15.02
+	Hs
		254330 CCR6_HUMAN (15-344): 5.11e-64: 209: 24.85		ATP9A_HUMAN (3-1118): 0: 746: 27.99
+	Hs
		619202 AGTR1_HUMAN (5-340): 4.07e-72: 229: 25.22		AT2B4_HUMAN (11-1207): 0: 721: 15.27
+	Hs
		895608 CXCR4_HUMAN (7-311): 7.44e-68: 218: 27.60		AT2B2_HUMAN (6-1207): 0: 730: 14.69
+	Hs
		208453 OX2R_HUMAN (8-344): 2.03e-66: 217: 17.73		AT2B2_HUMAN (6-1207): 0: 730: 14.69
+	Hs
		781053 OPRX_HUMAN (5-323): 4.51e-67: 217: 22.98		AT2B2_HUMAN (6-1207): 0: 730: 14.69
+	Hs
		428921 ADRB2_HUMAN (1-328): 9.21e-69: 222: 18.68		AT2B4_HUMAN (11-1207): 0: 721: 15.27
+	Hs
		619204 APJ_HUMAN (5-334): 5.38e-69: 222: 23.60		AT2B4_HUMAN (11-1207): 0: 721: 15.27
+	Hs
		966868 LPAR4_HUMAN (8-341): 2.1e-65: 212: 52.99		AT2B2_HUMAN (6-1207): 0: 730: 14.69
+	Hs
		208448 OX2R_HUMAN (8-344): 2.03e-66: 217: 17.73		AT2B4_HUMAN (11-1207): 0: 721: 15.27
+	Hs
		619206 OPRX_HUMAN (5-323): 4.51e-67: 217: 22.98		AT2B4_HUMAN (11-1207): 0: 721: 15.27
+	Hs
		619214 CCR6_HUMAN (15-344): 5.11e-64: 209: 24.85		AT2B4_HUMAN (11-1207): 0: 721: 15.27