HitPredict

Interactor 1: LPAR6 (P43657)
Lysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor)
Gene: LPAR6

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 344 Hs			1 178
+	Hs
		674844 AGTR1_HUMAN (5-340): 4.07e-72: 229: 25.22		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		974991 LPAR4_HUMAN (8-341): 2.1e-65: 212: 52.99		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		126584 P2Y10_HUMAN (12-312): 2.35e-45: 159: 31.46		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		626833 PAR1_HUMAN (23-302): 2.77e-43: 156: 34.16		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Mm
		578599 ADRB2_MOUSE (1-328): 1.31e-70: 227: 18.13		CAV3_MOUSE (35-177): 1.81e-76: 227: 65.73
+	Hs
		428989 ADRB2_HUMAN (1-328): 9.21e-69: 222: 18.68		CAV3_HUMAN (32-178): 1.22e-75: 224: 64.00
+	Hs
		782414 P2RY2_HUMAN (9-297): 1.06e-83: 259: 33.56		CAV2_HUMAN (53-177): 5.1e-59: 183: 40.80