HitPredict

Interactor 1: PRS6B (P43686)
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7)
Gene: PSMC4

Interactor 2: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 26186194, 28514442, 28292943, 33961781, 35271311, 19615732, 17353931, 32157086, 37071682
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~Prot_ATP_ID_OB, MitMem_reg~Prot_ATP_ID_OB
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 418
Hs

1 324
+ Dm
+ Dm
+ At
+ Dm
+ At
+ Sp
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Sp
+ Sp
+ Hs
+ At
+ Hs
+ Dm
+ Dm
+ Dm

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Last updated: 15 Jul 2024