HitPredict

Interactor 1: PRS6B (P43686)
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7)
Gene: PSMC4

Interactor 2: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 17573772
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 412
+	Hs
		913264 PRS10_HUMAN (35-417): 3.49e-126: 371: 40.47		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		907025 PRS8_HUMAN (38-418): 1.7e-122: 362: 42.26		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		906826 PRS4_HUMAN (32-412): 2.96e-120: 358: 49.09		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		684487 PRS6B_HUMAN (1-418): 3.22e-139: 406: 100.00		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Sc
		549721 PRS6B_YEAST (1-418): 7.52e-127: 374: 66.82		STI1_YEAST (221-371): 6.12e-25: 108: 19.21
+	Hs
		684603 PRS10_HUMAN (35-417): 3.49e-126: 371: 40.47		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		684594 PRS8_HUMAN (38-418): 1.7e-122: 362: 42.26		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		684593 PRS4_HUMAN (32-412): 2.96e-120: 358: 49.09		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00