HitPredict

Interactor 1: PRS6B (P43686)
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7)
Gene: PSMC4

Interactor 2: ZFN2A (Q8N6M9)
AN1-type zinc finger protein 2A
Gene: ZFAND2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 145
+	Hs
		798722 PRS6B_HUMAN (1-418): 3.22e-139: 406: 100.00		ZFN2B_HUMAN (1-145): 7.75e-67: 205: 59.31
+	Hs
		913324 PRS10_HUMAN (35-417): 3.49e-126: 371: 40.47		ZFN2B_HUMAN (1-145): 7.75e-67: 205: 59.31
+	Hs
		907107 PRS8_HUMAN (38-418): 1.7e-122: 362: 42.26		ZFN2B_HUMAN (1-145): 7.75e-67: 205: 59.31
+	Hs
		913314 PRS10_HUMAN (35-417): 3.49e-126: 371: 40.47		ZFN2A_HUMAN (1-145): 1.96e-62: 189: 100.00
+	Hs
		798719 PRS6B_HUMAN (1-418): 3.22e-139: 406: 100.00		ZFAN1_HUMAN (5-143): 3.79e-38: 132: 28.06
+	Sc
		703833 PRS6B_YEAST (1-418): 7.52e-127: 374: 66.82		CUZ1_YEAST (5-44): 1.41e-15: 72.9: 50.00
+	Sc
		771726 PRS4_YEAST (34-414): 2.92e-124: 368: 50.38		CUZ1_YEAST (5-44): 1.41e-15: 72.9: 50.00
+	Sc
		862664 PRS10_YEAST (12-418): 2.63e-120: 358: 40.34		CUZ1_YEAST (5-44): 1.41e-15: 72.9: 50.00