HitPredict

Interactor 1: GATA4 (P43694)
Transcription factor GATA-4 (GATA-binding factor 4)
Gene: GATA4

Interactor 2: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35182466
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 442 Hs			1 425
+	Mm
		570295 GATA1_MOUSE (52-419): 4.58e-38: 144: 32.88		RBBP7_MOUSE (1-425): 3.19e-115: 345: 99.77
+	Hs
		798841 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41
+	Hs
		997947 TRPS1_HUMAN (178-437): 1.43e-43: 165: 24.63		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Mm
		570294 GATA1_MOUSE (52-419): 4.58e-38: 144: 32.88		RBBP4_MOUSE (1-209): 1.59e-39: 148: 12.72
+	Hs
		620489 GATA3_HUMAN (43-387): 3.5e-35: 137: 35.17		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72