HitPredict

Interactor 1: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 28977666
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~Chromo, Chromo~PHD, Chromo~SNF2-rel_dom
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Hs

1 2000
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024