HitPredict

Interactor 1: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Interactor 2: LBR (Q14739)
Delta(14)-sterol reductase LBR (Delta-14-SR) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (C14SR) (Integral nuclear envelope inner membrane protein) (LMN2R) (Lamin-B receptor) (Sterol C14-reductase)
Gene: LBR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.648

Property	Details
Experiments	8663349, 15882967
Identification Methods	pull down, affinity chromatography technology, unspecified method, two hybrid, coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005635 - nuclear envelope
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 615
+	Mm
		1112417 CBX5_MOUSE (1-191): 1.9e-68: 208: 97.91		LBR_MOUSE (1-615): 0: 907: 78.12
+	Hs
		1026999 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		LBR_HUMAN (1-615): 0: 914: 100.00
+	Hs
		949783 CBX1_HUMAN (26-180): 2.32e-55: 175: 60.65		LBR_HUMAN (1-615): 0: 914: 100.00