HitPredict

Interactor 1: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Interactor 2: ZN562 (Q6V9R5)
Zinc finger protein 562
Gene: ZNF562

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 426
+	Hs
		800494 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN333_HUMAN (7-424): 0: 536: 33.12
+	Hs
		800425 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		Z585A_HUMAN (19-426): 6.73e-165: 484: 31.15
+	Hs
		800399 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN829_HUMAN (19-424): 1.22e-166: 476: 36.58
+	Hs
		800402 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN568_HUMAN (66-426): 6.32e-163: 474: 37.16
+	Hs
		800410 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN678_HUMAN (55-406): 5.06e-160: 462: 37.60
+	Hs
		800409 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN569_HUMAN (34-426): 1.58e-145: 431: 34.33
+	Hs
		800406 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		Z585B_HUMAN (17-426): 1.05e-131: 398: 32.88
+	Hs
		563302 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZNF16_HUMAN (144-426): 9.97e-113: 347: 37.50
+	Hs
		800424 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZFP1_HUMAN (35-426): 9.68e-82: 258: 39.95
+	Hs
		800462 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN561_HUMAN (83-292): 1.08e-75: 245: 29.95
+	Hs
		800465 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN557_HUMAN (92-285): 1.71e-64: 214: 30.35
+	Hs
		728565 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZNF93_HUMAN (127-399): 1.6e-61: 211: 43.89
+	Hs
		67855 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN724_HUMAN (56-175): 1.33e-38: 149: 14.96
+	Hs
		800355 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN543_HUMAN (58-164): 5.09e-30: 123: 17.43
+	Hs
		64158 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN726_HUMAN (58-148): 2.66e-28: 119: 12.90
+	Hs
		800509 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN426_HUMAN (81-198): 2.73e-25: 110: 21.60
+	Hs
		58857 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		A2VDJ6_HUMAN (80-153): 9.02e-15: 77.9: 17.11
+	Hs
		549158 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		ZN250_HUMAN (56-123): 1.55e-19: 92.8: 8.82
+	Hs
		800459 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZFP82_HUMAN (127-257): 1.83e-13: 73.9: 33.82
+	Hs
		800439 CBX5_HUMAN (1-191): 1.24e-68: 209: 100.00		ZN627_HUMAN (112-264): 6.31e-13: 72: 27.50