HitPredict

Interactor 1: CBX5 (P45973)
Chromobox protein homolog 5 (Antigen p25) (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Interactor 2: SENP7 (Q9BQF6)
Sentrin-specific protease 7 (EC 3.4.22.-) (SUMO-1-specific protease 2) (Sentrin/SUMO-specific protease SENP7)
Gene: SENP7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	27705803, 24018422, 20562864
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 1050
+	Hs
		1027222 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		SENP7_HUMAN (1-1050): 0: 1109: 100.00
+	Mm
		1143031 CBX5_MOUSE (1-191): 1.9e-68: 208: 97.91		SENP7_MOUSE (1-1049): 0: 1068: 69.65
+	Mm
		613032 CBX3_MOUSE (1-181): 6.23e-62: 191: 60.22		SENP7_MOUSE (1-1049): 0: 1068: 69.65
+	Mm
		949950 CBX1_MOUSE (26-180): 2.32e-55: 175: 60.65		SENP7_MOUSE (1-1049): 0: 1068: 69.65
+	Hs
		316153 CBX6_HUMAN (11-103): 2.2e-24: 100: 31.18		SENP3_HUMAN (629-965): 5.55e-74: 257: 12.47
+	Hs
		1027246 CBX3_HUMAN (1-181): 3.06e-62: 192: 60.22		SENP6_HUMAN (911-1046): 1.23e-35: 149: 53.68
+	Hs
		316126 CBX6_HUMAN (11-103): 2.2e-24: 100: 31.18		SENP5_HUMAN (591-965): 1.31e-55: 209: 11.72