Interactor 1: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Interactor 2: MP2K1 (Q02750)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: MAP2K1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.27 1.00 0.527

The method score is based on:

Property Details
Experiments 16533805
Identification Methods unspecified method
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006468 - protein phosphorylation
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 427
Hs

1 393
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Last updated: 15 Jul 2024