HitPredict

Interactor 1: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Interactor 2: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	8621542
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 619
+	Hs
		625382 CDK2_HUMAN (23-329): 1.82e-136: 394: 33.23		REL_HUMAN (1-619): 0: 692: 100.00
+	Hs
		864857 MK10_HUMAN (1-427): 6.5e-163: 468: 90.16		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		800766 MK08_HUMAN (1-427): 6.2e-164: 469: 100.00		NFAC3_HUMAN (1-610): 1.34e-128: 406: 15.35
+	Hs
		800876 MK09_HUMAN (1-427): 5.18e-163: 467: 80.80		NFAC3_HUMAN (1-610): 1.34e-128: 406: 15.35
+	Hs
		978772 MK14_HUMAN (4-365): 2.33e-130: 381: 46.03		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		800782 MK08_HUMAN (1-427): 6.2e-164: 469: 100.00		NFAC4_HUMAN (1-491): 7.19e-90: 299: 14.43
+	Hs
		800888 MK09_HUMAN (1-427): 5.18e-163: 467: 80.80		NFAC4_HUMAN (1-491): 7.19e-90: 299: 14.43
+	Hs
		800773 MK08_HUMAN (1-427): 6.2e-164: 469: 100.00		NFAC2_HUMAN (1-504): 1.26e-88: 296: 14.84
+	Hs
		800884 MK09_HUMAN (1-427): 5.18e-163: 467: 80.80		NFAC2_HUMAN (1-504): 1.26e-88: 296: 14.84
+	Hs
		658900 MK01_HUMAN (20-359): 2.94e-84: 263: 42.98		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89