HitPredict

Interactor 1: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Interactor 2: NFAC2 (Q13469)
Nuclear factor of activated T-cells, cytoplasmic 2 (NF-ATc2) (NFATc2) (NFAT pre-existing subunit) (NF-ATp) (T-cell transcription factor NFAT1)
Gene: NFATC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15184502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010628 - positive regulation of gene expression
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 925
+	Hs
		800884 MK09_HUMAN (1-427): 5.18e-163: 467: 80.80		NFAC2_HUMAN (1-925): 0: 860: 100.00
+	Hs
		800766 MK08_HUMAN (1-427): 6.2e-164: 469: 100.00		NFAC3_HUMAN (25-921): 0: 707: 32.85
+	Hs
		800876 MK09_HUMAN (1-427): 5.18e-163: 467: 80.80		NFAC3_HUMAN (25-921): 0: 707: 32.85
+	Hs
		800782 MK08_HUMAN (1-427): 6.2e-164: 469: 100.00		NFAC4_HUMAN (26-919): 0: 574: 33.78
+	Hs
		800888 MK09_HUMAN (1-427): 5.18e-163: 467: 80.80		NFAC4_HUMAN (26-919): 0: 574: 33.78
+	Hs
		864857 MK10_HUMAN (1-427): 6.5e-163: 468: 90.16		TF65_HUMAN (394-918): 3.44e-127: 397: 17.89
+	Hs
		800754 MK08_HUMAN (1-427): 6.2e-164: 469: 100.00		REL_HUMAN (408-887): 1.1e-124: 392: 15.77
+	Hs
		625382 CDK2_HUMAN (23-329): 1.82e-136: 394: 33.23		REL_HUMAN (408-887): 1.1e-124: 392: 15.77
+	Hs
		978772 MK14_HUMAN (4-365): 2.33e-130: 381: 46.03		TF65_HUMAN (394-918): 3.44e-127: 397: 17.89
+	Hs
		658900 MK01_HUMAN (20-359): 2.94e-84: 263: 42.98		TF65_HUMAN (394-918): 3.44e-127: 397: 17.89