HitPredict

Interactor 1: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Interactor 2: WWOX (Q9NZC7)
WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase) (Short chain dehydrogenase/reductase family 41C member 1)
Gene: WWOX

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	18371080, 12514174
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019899 - enzyme binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 414
+	Hs
		800951 MK09_HUMAN (1-427): 5.18e-163: 467: 80.80		WWOX_HUMAN (1-414): 3.42e-136: 397: 100.00
+	Mm
		1265126 MK08_MOUSE (1-381): 7.75e-152: 437: 99.48		WWOX_MOUSE (1-414): 6.4e-137: 399: 93.72
+	Hs
		659072 MK01_HUMAN (20-359): 2.94e-84: 263: 42.98		WWOX_HUMAN (1-414): 3.42e-136: 397: 100.00