HitPredict

Interactor 1: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Interactor 2: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26949251
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008283 - cell population proliferation GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 3256 Hs			1 184
+	Hs
		801060 KI67_HUMAN (1-3256): 0: 1046: 100.00		RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98
+	Ce
		136793 UNC89_CAEEL (45-2098): 4.04e-14: 82: 7.38		RAC1_CAEEL (1-184): 8.89e-69: 209: 27.55
+	Hs
		914253 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98
+	Hs
		925204 ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47		RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55
+	Hs
		297823 K0754_HUMAN (1009-1559): 3.82e-09: 65.1: 14.44		RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55
+	Hs
		350694 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		350405 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		349253 ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47		RASH_HUMAN (1-167): 1.22e-55: 175: 57.49
+	Hs
		350083 ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		297806 K0754_HUMAN (1009-1559): 3.82e-09: 65.1: 14.44		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		297805 K0754_HUMAN (1009-1559): 3.82e-09: 65.1: 14.44		RASN_HUMAN (1-167): 5.03e-54: 171: 56.89