HitPredict

Interactor 1: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Interactor 2: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26949251
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 3256 Hs			1 7570
+	Hs
		801013 KI67_HUMAN (1-3256): 0: 1046: 100.00		UTRN_HUMAN (264-1530): 1.26e-14: 84.8: 9.65
+	Hs
		944680 MAP1A_HUMAN (139-2564): 8.72e-104: 377: 10.33		PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19
+	Hs
		807656 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		EPIPL_HUMAN (1651-1891): 1.02e-10: 71.7: 20.73
+	Hs
		807779 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		SYNE1_HUMAN (147-1832): 6.65e-10: 69: 8.83
+	Hs
		963451 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95
+	Hs
		521586 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00
+	Hs
		513849 ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47		DMD_HUMAN (383-1643): 8.98e-27: 124: 11.75
+	Mm
		561172 ANK2_MOUSE (804-3071): 1.44e-27: 126: 8.59		SPTN1_MOUSE (268-1534): 1.96e-10: 70.7: 11.75
+	Hs
		963292 ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47		SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95
+	Hs
		965174 ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47		MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05
+	Hs
		1068702 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19
+	Hs
		885330 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		EPIPL_HUMAN (1651-1891): 1.02e-10: 71.7: 20.73
+	Hs
		164604 ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47		SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91
+	Hs
		993278 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		ACTN3_HUMAN (453-929): 1.33e-11: 74.3: 10.26
+	Hs
		965102 ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47		SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42
+	Dm
		574825 TITIN_DROME (757-3249): 1.04e-11: 74: 12.72		ACTN_DROME (3594-4062): 2.01e-11: 73.6: 9.98
+	Hs
		551790 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		DESP_HUMAN (1555-1738): 2.9e-09: 67: 28.50
+	Hs
		1068678 MXRA5_HUMAN (644-1631): 6.71e-10: 67.8: 14.34		PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19