HitPredict

Interactor 1: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	12485163, 34079125
Identification Methods	two hybrid, pull down, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 3256 Hs			1 183
+	Hs
		801081 KI67_HUMAN (1-3256): 0: 1046: 100.00		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		123199 KI67_HUMAN (1-3256): 0: 1046: 100.00		CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52
+	Hs
		1026998 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1056829 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		CBX2_HUMAN (20-117): 5.97e-25: 102: 27.00
+	Hs
		1027333 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1027054 NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		800421 NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		949814 NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33