HitPredict

Interactor 1: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Interactor 2: GRB10 (Q13322)
Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR)
Gene: GRB10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	26949251
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FHA~PH
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 3256 Hs			1 594
+	Hs
		412078 KI67_HUMAN (1-3256): 0: 1046: 100.00		FYN_HUMAN (441-591): 5.64e-47: 174: 20.38
+	Hs
		522847 KI67_HUMAN (1-3256): 0: 1046: 100.00		SRC_HUMAN (443-590): 9.55e-47: 174: 22.08
+	Hs
		789101 KI67_HUMAN (1-3256): 0: 1046: 100.00		FRK_HUMAN (438-594): 3.18e-45: 169: 20.38
+	Hs
		788977 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		TEC_HUMAN (293-590): 2.81e-52: 191: 12.33
+	Hs
		924473 MAP1A_HUMAN (139-2564): 8.72e-104: 377: 10.33		GRB2_HUMAN (489-575): 3.64e-20: 91.4: 29.89
+	Hs
		807680 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		GRB2_HUMAN (489-575): 3.64e-20: 91.4: 29.89
+	Hs
		855812 BD1L1_HUMAN (98-2862): 2.37e-19: 99.1: 9.63		VAV2_HUMAN (40-588): 1.7e-95: 313: 12.26
+	Hs
		855816 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		VAV2_HUMAN (40-588): 1.7e-95: 313: 12.26
+	Hs
		996575 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		ITK_HUMAN (293-589): 1.9e-60: 213: 15.47
+	Hs
		434084 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		LYN_HUMAN (409-593): 7.45e-46: 171: 17.19
+	Hs
		433701 ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47		LYN_HUMAN (409-593): 7.45e-46: 171: 17.19
+	Hs
		924760 PRG4_HUMAN (64-1059): 1.94e-35: 151: 8.58		GRB2_HUMAN (489-575): 3.64e-20: 91.4: 29.89
+	Hs
		64077 L37A2_HUMAN (2491-3207): 9.71e-10: 67.1: 12.98		SRC_HUMAN (443-590): 9.55e-47: 174: 22.08
+	Hs
		297808 K0754_HUMAN (1009-1559): 3.82e-09: 65.1: 14.44		LYN_HUMAN (409-593): 7.45e-46: 171: 17.19
+	Hs
		820875 PRC2A_HUMAN (513-2601): 5.1e-21: 104: 7.93		GRB2_HUMAN (489-575): 3.64e-20: 91.4: 29.89
+	Hs
		924484 ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47		GRB2_HUMAN (489-575): 3.64e-20: 91.4: 29.89