HitPredict

Interactor 1: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Interactor 2: CUL7 (Q14999)
Cullin-7 (CUL-7)
Gene: CUL7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24711643
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007088 - regulation of mitotic nuclear division
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 3256 Hs			1 1698
+	Hs
		944679 MAP1A_HUMAN (139-2564): 8.72e-104: 377: 10.33		CUL7_HUMAN (1-1698): 0: 2861: 100.00
+	Hs
		1056833 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		CUL7_HUMAN (1-1698): 0: 2861: 100.00
+	Hs
		807727 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		CUL7_HUMAN (1-1698): 0: 2861: 100.00
+	Hs
		820925 PRC2A_HUMAN (513-2601): 5.1e-21: 104: 7.93		CUL7_HUMAN (1-1698): 0: 2861: 100.00
+	Hs
		1061691 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		CUL7_HUMAN (1-1698): 0: 2861: 100.00
+	Hs
		1061523 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		CUL7_HUMAN (1-1698): 0: 2861: 100.00
+	Hs
		319754 KI67_HUMAN (1-3256): 0: 1046: 100.00		HERC2_HUMAN (838-982): 1.36e-38: 161: 36.55
+	Hs
		1057026 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		APC10_HUMAN (830-969): 1.42e-51: 181: 23.45
+	Hs
		319840 MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14		HERC2_HUMAN (838-982): 1.36e-38: 161: 36.55
+	Mm
		1118155 ANK2_MOUSE (804-3071): 1.44e-27: 126: 8.59		HERC2_MOUSE (838-982): 5.36e-38: 159: 34.48