HitPredict

Interactor 1: NOP2 (P46087)
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120)
Gene: NOP2

Interactor 2: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 812 Hs			1 688
+	Hs
		802268 NOP2_HUMAN (1-812): 0: 835: 100.00		SRPK3_HUMAN (450-687): 1.19e-63: 223: 66.39
+	Hs
		802247 NOP2_HUMAN (1-812): 0: 835: 100.00		CDK12_HUMAN (291-687): 5.8e-54: 203: 13.17