HitPredict

Interactor 1: GPR3 (P46089)
G-protein coupled receptor 3 (ACCA orphan receptor)
Gene: GPR3

Interactor 2: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	24069330
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	7tm_1~Arrestin_C, 7tm_1~Arrestin_N
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 418
+	Hs
		827170 MSHR_HUMAN (46-314): 1.08e-68: 219: 27.27		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		441649 ADRB1_HUMAN (4-314): 3.69e-66: 217: 19.58		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		827197 MTR1L_HUMAN (30-318): 1.03e-62: 211: 18.81		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		781016 OPRD_HUMAN (9-326): 2.88e-64: 209: 18.34		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		428933 ADRB2_HUMAN (11-329): 8.11e-73: 232: 19.94		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Rn
		663954 Q8VBU7_RAT (7-329): 2.79e-74: 236: 18.66		ARRB2_RAT (1-407): 0: 616: 75.00
+	Hs
		685913 MSHR_HUMAN (46-314): 1.08e-68: 219: 27.27		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		441648 ADRB1_HUMAN (4-314): 3.69e-66: 217: 19.58		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		685837 GPR3_HUMAN (1-330): 4.1e-68: 217: 100.00		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		685822 OPRD_HUMAN (9-326): 2.88e-64: 209: 18.34		ARRB2_HUMAN (1-407): 0: 626: 76.15