Interactor 1: 5HT3A (P46098)
5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)
Gene: HTR3A

Interactor 2: 5HT3A (P46098)
5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)
Gene: HTR3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.584

The method score is based on:

Property Details
Experiments 16116092
Identification Methods atomic force microscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0005231 - excitatory extracellular ligand-gated monoatomic ion channel activity
GO:0005886 - plasma membrane
GO:0007210 - serotonin receptor signaling pathway
GO:0022848 - acetylcholine-gated monoatomic cation-selective channel activity
GO:0022850 - serotonin-gated monoatomic cation channel activity
and 10 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 478
Hs

1 478
+ Gg
+ Hs
+ Gg
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+ Gg
+ Gg
+ Hs
+ Gg
+ Mm
+ Gg
+ Gg
+ Hs
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+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024