HitPredict

Interactor 1: 5HT3A (P46098)
5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)
Gene: HTR3A

Interactor 2: ASTRB (Q3KR37)
Protein Aster-B (GRAM domain-containing protein 1B)
Gene: GRAMD1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 478 Hs			1 738
+	Hs
		687008 ACHA3_HUMAN (30-476): 0: 530: 22.69		ASTRA_HUMAN (9-725): 0: 783: 46.78
+	Hs
		570874 ACHB2_HUMAN (25-478): 2.88e-177: 508: 24.68		ASTRA_HUMAN (9-725): 0: 783: 46.78
+	Hs
		677162 ACHB4_HUMAN (8-478): 2.26e-174: 500: 25.30		ASTRA_HUMAN (9-725): 0: 783: 46.78
+	Hs
		802371 5HT3A_HUMAN (1-478): 2.75e-173: 497: 100.00		ASTRA_HUMAN (9-725): 0: 783: 46.78
+	Hs
		1287054 ACHA9_HUMAN (4-469): 2.47e-154: 449: 27.29		ASTRA_HUMAN (9-725): 0: 783: 46.78
+	Hs
		1263260 5HT3C_HUMAN (46-473): 3.65e-88: 278: 37.59		ASTRA_HUMAN (9-725): 0: 783: 46.78
+	Hs
		798483 ACHA4_HUMAN (355-475): 1.85e-27: 117: 19.01		ASTRB_HUMAN (1-738): 0: 915: 100.00
+	Hs
		798550 ACHA4_HUMAN (355-475): 1.85e-27: 117: 19.01		ASTRA_HUMAN (9-725): 0: 783: 46.78