Interactor 1: 5HT3A (P46098)
5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)
Gene: HTR3A
Interactor 2: 5HT3D (Q70Z44)
5-hydroxytryptamine receptor 3D (5-HT3-D) (5-HT3D) (Serotonin receptor 3D)
Gene: HTR3D
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.44 | 1.00 | 0.665 |
The method score is based on:
Property | Details |
---|---|
Experiments | 17392525 |
Identification Methods | anti bait coimmunoprecipitation, pull down |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb |
Common GO terms | GO:0005231 - excitatory extracellular ligand-gated monoatomic ion channel activity GO:0005886 - plasma membrane GO:0007210 - serotonin receptor signaling pathway GO:0022848 - acetylcholine-gated monoatomic cation-selective channel activity GO:0022850 - serotonin-gated monoatomic cation channel activity and 7 others more... |
Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024