HitPredict

Interactor 1: 5HT3A (P46098)
5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)
Gene: HTR3A

Interactor 2: GOLI (Q86XS8)
E3 ubiquitin-protein ligase RNF130 (EC 2.3.2.27) (Goliath homolog) (H-Goliath) (RING finger protein 130) (RING-type E3 ubiquitin transferase RNF130)
Gene: RNF130

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 478 Hs			1 419
+	Hs
		570854 ACHB2_HUMAN (25-478): 2.88e-177: 508: 24.68		GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00
+	Hs
		677149 ACHB4_HUMAN (8-478): 2.26e-174: 500: 25.30		GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00
+	Hs
		802346 5HT3A_HUMAN (1-478): 2.75e-173: 497: 100.00		SYVN1_HUMAN (17-312): 1.08e-56: 198: 14.38
+	Hs
		362150 ACHA_HUMAN (14-469): 1.65e-159: 461: 25.27		SYVN1_HUMAN (17-312): 1.08e-56: 198: 14.38
+	Hs
		989627 ACHD_HUMAN (26-476): 6.27e-154: 449: 24.17		SYVN1_HUMAN (17-312): 1.08e-56: 198: 14.38
+	Hs
		1204801 5HT3C_HUMAN (46-473): 3.65e-88: 278: 37.59		GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00
+	Hs
		1198679 ACH10_HUMAN (36-471): 5.02e-152: 442: 29.93		SYVN1_HUMAN (17-312): 1.08e-56: 198: 14.38
+	Hs
		677184 ACHB4_HUMAN (8-478): 2.26e-174: 500: 25.30		RN215_HUMAN (207-309): 2.58e-26: 111: 32.74
+	Hs
		61238 5HT3E_HUMAN (46-473): 8.32e-93: 290: 39.03		AMFR_HUMAN (2-346): 7.99e-45: 166: 13.50
+	Hs
		798572 ACHA4_HUMAN (355-475): 1.85e-27: 117: 19.01		RN167_HUMAN (46-366): 3.66e-56: 190: 21.10