HitPredict

Interactor 1: ATRX (P46100)
Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf-HX)
Gene: ATRX

Interactor 2: RAD51 (Q06609)
DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)
Gene: RAD51

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.759

The method score is based on:

Property Details
Experiments 12750285, 12205100, 32457312, 19671661, 28976962, 16990250, 10851248, 32876692, 15466868, 9321665, 23801766
Identification Methods affinity chromatography technology, pull down, far western blotting, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000228 - nuclear chromosome
GO:0000781 - chromosome, telomeric region
GO:0003682 - chromatin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 7 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2492
Hs

1 339
+ Hs
+ Sc
+ Mm
+ Hs
+ Hs
+ Sp
+ At
+ Sp
+ Hs
+ Ce
+ Ce
+ Sc
+ Hs
+ Ce
+ Sc
+ Sc
+ Sp
+ Sc

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Last updated: 15 Jul 2024