Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK
Interactor 2: RPGF1 (Q13905)
Rap guanine nucleotide exchange factor 1 (CRK SH3-binding GNRP) (Guanine nucleotide-releasing factor 2) (Protein C3G)
Gene: RAPGEF1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.763 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10464310, 9564038, 31980649, 7512734, 33961781, 36720192, 8943292, 7531694, 19380743, 18835194, 17515907, 17474147, 19001122, unassigned2173, 8621483 |
| Identification Methods | affinity chromatography technology, pull down, far western blotting, peptide array, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0017124 - SH3 domain binding and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
