HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: K2C79 (Q5XKE5)
Keratin, type II cytoskeletal 79 (Cytokeratin-79) (CK-79) (Keratin-6-like) (Keratin-6L) (Keratin-79) (K79) (Type-II keratin Kb38)
Gene: KRT79

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 304 Hs			1 535
+	Hs
		729048 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K22E_HUMAN (114-460): 1.25e-156: 462: 70.03
+	Hs
		409026 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C8_HUMAN (114-492): 1.6e-141: 418: 61.48
+	Hs
		409124 DNMBP_HUMAN (119-293): 5.7e-46: 168: 29.35		K2C8_HUMAN (114-492): 1.6e-141: 418: 61.48
+	Hs
		729063 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		K22E_HUMAN (114-460): 1.25e-156: 462: 70.03
+	Hs
		444533 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		K2C7_HUMAN (89-469): 7.05e-142: 419: 62.69
+	Hs
		409046 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		K2C8_HUMAN (114-492): 1.6e-141: 418: 61.48
+	Hs
		802647 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C73_HUMAN (18-534): 1.69e-93: 297: 53.73
+	Hs
		802644 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C1B_HUMAN (36-476): 1.35e-81: 267: 59.48
+	Hs
		380448 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C6B_HUMAN (1-481): 1.03e-76: 253: 60.64
+	Hs
		531539 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C5_HUMAN (3-460): 6.84e-75: 249: 63.51
+	Hs
		359471 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C6A_HUMAN (1-481): 5.91e-72: 241: 61.23
+	Hs
		517743 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C3_HUMAN (114-462): 3.51e-65: 225: 73.93
+	Hs
		802568 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K22O_HUMAN (5-472): 5.28e-64: 222: 58.09
+	Hs
		924469 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		KRT83_HUMAN (5-518): 3.36e-93: 294: 43.19
+	Hs
		213936 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		KRT86_HUMAN (5-523): 1.04e-90: 288: 42.15
+	Hs
		924470 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		KRT85_HUMAN (2-510): 1.4e-88: 283: 43.14
+	Hs
		531551 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		K2C5_HUMAN (3-460): 6.84e-75: 249: 63.51
+	Hs
		359480 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		K2C6A_HUMAN (1-481): 5.91e-72: 241: 61.23
+	Mm
		1060206 GRB2_MOUSE (135-297): 1.43e-25: 103: 15.67		Q148Q7_MOUSE (2-470): 7.97e-64: 219: 58.81
+	Mm
		1141145 GRB2_MOUSE (135-297): 1.43e-25: 103: 15.67		Q8BIS2_MOUSE (2-470): 9.71e-64: 218: 58.81