HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: KCD17 (Q8N5Z5)
BTB/POZ domain-containing protein KCTD17
Gene: KCTD17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	25814554, unassigned1126
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 314
+	Hs
		562656 PLCG2_HUMAN (1-301): 1.03e-25: 109: 15.89		KCD17_HUMAN (1-314): 8.44e-102: 302: 100.00
+	Hs
		802680 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		BACD1_HUMAN (4-178): 1.04e-45: 159: 28.98
+	Hs
		209114 NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00		KCD17_HUMAN (1-314): 8.44e-102: 302: 100.00
+	Hs
		924759 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		KCNB2_HUMAN (3-260): 9.99e-74: 245: 17.91
+	Hs
		924556 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		BACD2_HUMAN (5-203): 2.51e-46: 160: 26.00
+	Hs
		924719 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		SHKB1_HUMAN (14-122): 3.69e-38: 145: 44.95
+	Hs
		1330034 ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86		BACD3_HUMAN (3-203): 5.32e-48: 164: 27.23
+	Hs
		1285189 SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22		BACD3_HUMAN (3-203): 5.32e-48: 164: 27.23
+	Hs
		1252625 SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22		SHKB1_HUMAN (14-122): 3.69e-38: 145: 44.95
+	Hs
		1285234 SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22		KCTD3_HUMAN (13-131): 1.21e-36: 140: 46.22