HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: ZBTB9 (Q96C00)
Zinc finger and BTB domain-containing protein 9
Gene: ZBTB9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 473
+	Hs
		802757 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		ZKSC7_HUMAN (104-297): 6.91e-37: 146: 9.65
+	Hs
		169693 GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17		ZBT7B_HUMAN (16-458): 1.24e-68: 230: 19.40
+	Hs
		169705 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		ZBT7B_HUMAN (16-458): 1.24e-68: 230: 19.40
+	Hs
		924976 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		ZBT12_HUMAN (16-462): 3.58e-62: 210: 22.94
+	Hs
		169691 NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00		ZBT7B_HUMAN (16-458): 1.24e-68: 230: 19.40
+	Hs
		169714 Q5JPT6_HUMAN (114-192): 4.08e-10: 62.5: 22.22		ZBT7B_HUMAN (16-458): 1.24e-68: 230: 19.40
+	Hs
		169725 SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22		ZBT7B_HUMAN (16-458): 1.24e-68: 230: 19.40
+	Hs
		209195 NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00		ZBT12_HUMAN (16-462): 3.58e-62: 210: 22.94
+	Hs
		562668 PLCG2_HUMAN (1-301): 1.03e-25: 109: 15.89		ZKSC7_HUMAN (104-297): 6.91e-37: 146: 9.65
+	Mm
		1145226 PLCG2_MOUSE (11-301): 1.34e-25: 108: 16.40		ZBT7B_MOUSE (410-468): 1.06e-14: 78.4: 30.00
+	Hs
		70959 NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00		ZBT42_HUMAN (184-473): 2.16e-22: 101: 15.26
+	Ce
		105896 Q9U2T9_CAEEL (182-300): 9.9e-11: 64.7: 13.22		KLHL8_CAEEL (17-175): 4.02e-10: 64.3: 27.98