HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: MINT (Q96T58)
Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog)
Gene: SPEN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	35044719, 17474147
Identification Methods	unspecified method, peptide array, phage display
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 3664
+	Hs
		581042 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		MINT_HUMAN (1-3664): 0: 1099: 100.00
+	Hs
		924808 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		MINT_HUMAN (1-3664): 0: 1099: 100.00
+	Hs
		557777 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		MINT_HUMAN (1-3664): 0: 1099: 100.00
+	Hs
		924473 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		MAP1A_HUMAN (1594-3632): 5.67e-29: 131: 8.94
+	Hs
		924484 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		ANK2_HUMAN (809-3143): 4.11e-25: 118: 9.30
+	Hs
		1302717 VAV3_HUMAN (11-189): 1.56e-33: 131: 26.15		RBM15_HUMAN (3336-3649): 5.22e-14: 81.1: 26.65
+	Ce
		666211 SEM5_CAEEL (135-291): 6.58e-25: 101: 14.83		Q17350_CAEEL (215-437): 1.02e-16: 89.5: 11.89
+	Hs
		557660 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		ANK2_HUMAN (809-3143): 4.11e-25: 118: 9.30
+	Hs
		516450 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		PABP1_HUMAN (6-156): 2.77e-09: 65.2: 13.48
+	Ce
		136804 VAV_CAEEL (13-194): 4.87e-22: 98.4: 23.94		UNC89_CAEEL (675-1148): 3.12e-09: 65.7: 17.91
+	Hs
		1031420 SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22		PABP4_HUMAN (6-131): 2.64e-15: 84.9: 15.03
+	Hs
		516629 SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22		PABP1_HUMAN (6-156): 2.77e-09: 65.2: 13.48