HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: PRAX (Q9BXM0)
Periaxin
Gene: PRX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 1461
+	Hs
		557785 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		PRAX_HUMAN (1-1461): 2.48e-142: 475: 100.00
+	Hs
		924522 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		AHNK_HUMAN (18-1461): 1.49e-70: 265: 14.58
+	Hs
		802709 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		MINT_HUMAN (68-1443): 3.77e-27: 123: 8.80
+	Hs
		924473 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		MAP1A_HUMAN (115-1443): 1.03e-40: 167: 7.11
+	Hs
		581042 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		MINT_HUMAN (68-1443): 3.77e-27: 123: 8.80
+	Hs
		924808 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		MINT_HUMAN (68-1443): 3.77e-27: 123: 8.80
+	Hs
		855816 VAV2_HUMAN (2-191): 3.44e-29: 119: 19.74		TITIN_HUMAN (404-1460): 7.5e-19: 96.1: 10.07
+	Hs
		924760 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		PRG4_HUMAN (820-1451): 9.02e-21: 101: 8.70
+	Hs
		517796 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		NFH_HUMAN (928-1459): 1.81e-20: 100: 9.35
+	Ce
		136804 VAV_CAEEL (13-194): 4.87e-22: 98.4: 23.94		UNC89_CAEEL (629-1431): 2.3e-17: 91.1: 10.21
+	Hs
		557777 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		MINT_HUMAN (68-1443): 3.77e-27: 123: 8.80
+	Hs
		1056926 SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22		MDC1_HUMAN (28-1460): 1.59e-26: 120: 8.56
+	Hs
		203218 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		SYNJ1_HUMAN (304-747): 2.81e-11: 70.9: 10.50
+	Hs
		203208 NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00		SYNJ1_HUMAN (304-747): 2.81e-11: 70.9: 10.50
+	Hs
		203228 ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87		SYNJ1_HUMAN (304-747): 2.81e-11: 70.9: 10.50
+	Hs
		203241 SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22		SYNJ1_HUMAN (304-747): 2.81e-11: 70.9: 10.50
+	Hs
		1285227 SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22		SRRM2_HUMAN (2-1070): 7.84e-10: 66.1: 8.79