HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: SH2B1 (Q9NRF2)
SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B)
Gene: SH2B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 35044719
Identification Methods unspecified method, phage display
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, PH~SH3_1, SH2~SH3_1, SH2~SH3_2
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 304
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024