HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: PCDA2 (Q9Y5H9)
Protocadherin alpha-2 (PCDH-alpha-2)
Gene: PCDHA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 948
+	Hs
		802800 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		PCDA1_HUMAN (1-948): 0: 1107: 83.26
+	Hs
		802776 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		PCDA7_HUMAN (1-948): 0: 1106: 80.17
+	Hs
		802796 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		PCDA3_HUMAN (1-948): 0: 1106: 82.53
+	Hs
		802777 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		PCDA6_HUMAN (1-948): 0: 1104: 80.63
+	Hs
		802794 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		PCDA8_HUMAN (1-948): 0: 1104: 79.37
+	Hs
		802798 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		PCDAB_HUMAN (1-948): 0: 1101: 81.16
+	Hs
		802795 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		PCDA5_HUMAN (24-948): 0: 1096: 82.05
+	Hs
		802793 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		PCDA9_HUMAN (1-948): 0: 1082: 80.00
+	Hs
		802778 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		PCDAC_HUMAN (1-948): 0: 1079: 80.49
+	Hs
		802799 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		PCDAA_HUMAN (22-948): 0: 1079: 81.16
+	Hs
		924987 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		PCDB5_HUMAN (1-801): 0: 923: 38.00