HitPredict

Interactor 1: CRKL (P46109)
Crk-like protein
Gene: CRKL

Interactor 2: Q5JVZ5 (Q5JVZ5)
Engulfment and cell motility 2 (HCG1811050, isoform CRA_b)
Gene: ELMO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 303 Hs			1 718
+	Hs
		802890 CRKL_HUMAN (1-303): 6.11e-73: 228: 100.00		ELMO2_HUMAN (1-718): 0: 1047: 99.72
+	Hs
		802880 CRKL_HUMAN (1-303): 6.11e-73: 228: 100.00		ELMO1_HUMAN (1-716): 0: 1009: 75.48
+	Hs
		802699 CRK_HUMAN (3-302): 8.95e-54: 179: 55.21		ELMO2_HUMAN (1-718): 0: 1047: 99.72
+	Hs
		802682 CRK_HUMAN (3-302): 8.95e-54: 179: 55.21		ELMO1_HUMAN (1-716): 0: 1009: 75.48
+	Hs
		802691 CRK_HUMAN (3-302): 8.95e-54: 179: 55.21		ELMO3_HUMAN (1-716): 0: 941: 50.63
+	Hs
		924793 GRB2_HUMAN (240-295): 1.72e-10: 61.8: 26.32		ELMO2_HUMAN (1-718): 0: 1047: 99.72
+	Mm
		1141144 GRB2_MOUSE (240-295): 1.96e-10: 61.4: 26.32		ELMO2_MOUSE (1-718): 0: 1038: 96.86
+	Hs
		924774 GRB2_HUMAN (240-295): 1.72e-10: 61.8: 26.32		ELMO3_HUMAN (1-716): 0: 941: 50.63
+	Ce
		1248330 CED2_CAEEL (1-298): 3.79e-38: 138: 27.10		CED12_CAEEL (27-711): 0: 674: 21.41