Interactor 1: CRKL (P46109)
Crk-like protein
Gene: CRKL

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 31046837, unassigned1853
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~SH2
Common GO terms GO:0001933 - negative regulation of protein phosphorylation
GO:0001934 - positive regulation of protein phosphorylation
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0007254 - JNK cascade
and 2 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 303
Hs

1 2527
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Ce
+ Hs
+ Mm

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Last updated: 15 Jul 2024