HitPredict

Interactor 1: CRKL (P46109)
Crk-like protein
Gene: CRKL

Interactor 2: M4K1 (Q92918)
Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (Hematopoietic progenitor kinase) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1)
Gene: MAP4K1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.702

The method score is based on:

Property Details
Experiments 32640226, 9891069, 9788432, 11279207
Identification Methods affinity chromatography technology, pull down, coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0007254 - JNK cascade
GO:0035556 - intracellular signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 303
Hs

1 833
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024