HitPredict

Interactor 1: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Interactor 2: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 34432599
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1132 Hs			1 207
+	Hs
		803478 BAG6_HUMAN (1-1132): 0: 597: 100.00		RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50
+	Hs
		803738 BAG6_HUMAN (1-1132): 0: 597: 100.00		RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15
+	Hs
		803476 BAG6_HUMAN (1-1132): 0: 597: 100.00		RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99
+	Hs
		803468 BAG6_HUMAN (1-1132): 0: 597: 100.00		RAB8A_HUMAN (1-205): 1.09e-78: 235: 31.73
+	Hs
		803763 BAG6_HUMAN (1-1132): 0: 597: 100.00		RAB9B_HUMAN (3-181): 1.97e-69: 212: 55.87
+	Hs
		803443 BAG6_HUMAN (1-1132): 0: 597: 100.00		RAB13_HUMAN (8-174): 6.65e-37: 129: 38.32
+	Sc
		350835 RL40A_YEAST (17-87): 6.63e-27: 108: 34.72		YPT1_YEAST (1-206): 8.02e-81: 241: 31.91
+	Hs
		257589 ANR17_HUMAN (89-826): 6.63e-26: 118: 12.00		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44
+	Hs
		845889 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		RAB13_HUMAN (8-174): 6.65e-37: 129: 38.32
+	Hs
		844472 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44