HitPredict

Interactor 1: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Interactor 2: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29180619
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1132 Hs			1 190
+	Hs
		584896 BAG6_HUMAN (1-1132): 0: 597: 100.00		RO52_HUMAN (120-187): 1.12e-11: 64.3: 34.78
+	Hs
		941557 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00
+	Hs
		941579 UBQL1_HUMAN (15-521): 2.36e-25: 114: 12.84		RNF4_HUMAN (1-190): 9.49e-57: 179: 100.00
+	At
		1352316 DSK2A_ARATH (2-480): 1.97e-32: 135: 15.56		PEX10_ARATH (56-189): 1.19e-23: 97.8: 17.78
+	At
		1352315 DSK2B_ARATH (2-472): 1.45e-30: 130: 15.63		PEX10_ARATH (56-189): 1.19e-23: 97.8: 17.78
+	Xl
		1140127 Q6DCM1_XENLA (16-542): 1.32e-26: 118: 13.37		Q5XGX4_XENLA (103-189): 1.43e-21: 88.6: 23.33
+	Hs
		1292361 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		RN185_HUMAN (126-189): 2.47e-20: 85.5: 31.34
+	Xl
		1140144 Q801P8_XENLA (2-494): 1.16e-24: 112: 13.79		Q5XGX4_XENLA (103-189): 1.43e-21: 88.6: 23.33
+	Hs
		1292358 UBQL4_HUMAN (6-549): 7.75e-26: 115: 11.19		RN185_HUMAN (126-189): 2.47e-20: 85.5: 31.34
+	Dm
		547949 RS27A_DROME (17-87): 2.18e-27: 111: 34.72		Q9VJB0_DROME (99-190): 2e-21: 89.3: 26.09
+	Dm
		574857 RL40_DROME (17-87): 9.53e-28: 111: 34.72		Q9VJB0_DROME (99-190): 2e-21: 89.3: 26.09
+	Xl
		1140130 Q6GMC1_XENLA (17-87): 2.18e-27: 111: 34.72		Q5XGX4_XENLA (103-189): 1.43e-21: 88.6: 23.33
+	Xl
		1140133 Q6GQF3_XENLA (17-87): 9.53e-28: 111: 34.72		Q5XGX4_XENLA (103-189): 1.43e-21: 88.6: 23.33
+	Hs
		1292364 UBQL1_HUMAN (15-521): 2.36e-25: 114: 12.84		RN185_HUMAN (126-189): 2.47e-20: 85.5: 31.34
+	Hs
		924117 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		RN185_HUMAN (126-189): 2.47e-20: 85.5: 31.34