HitPredict

Interactor 1: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Interactor 2: ATX2 (Q99700)
Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)
Gene: ATXN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.620

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1132 Hs			1 1313
+	Hs
		803742 BAG6_HUMAN (1-1132): 0: 597: 100.00		TARA_HUMAN (305-1312): 2.89e-16: 87.1: 10.79
+	Hs
		257690 ANR17_HUMAN (89-826): 6.63e-26: 118: 12.00		ATX2_HUMAN (1-1313): 1.72e-116: 397: 100.00
+	Hs
		867142 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		SC24C_HUMAN (1-235): 7.03e-47: 185: 20.00
+	Hs
		554259 MUC1_HUMAN (122-783): 1.91e-30: 132: 11.94		MUC1_HUMAN (699-1312): 1.2e-29: 130: 10.26
+	Hs
		867119 SC24C_HUMAN (380-696): 1.27e-39: 162: 24.18		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Mm
		1351630 PCLO_MOUSE (90-802): 1.36e-18: 94.4: 10.64		PCLO_MOUSE (966-1313): 9.21e-09: 62.5: 9.77
+	Dm
		113976 M9PB30_DROME (9-480): 2.03e-14: 80.9: 11.20		M9PB30_DROME (8-712): 1.36e-11: 71.7: 9.12
+	Hs
		1300971 CHD7_HUMAN (52-409): 9.99e-10: 65.5: 8.64		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47