HitPredict

Interactor 1: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Interactor 2: RNF5 (Q99942)
E3 ubiquitin-protein ligase RNF5 (EC 2.3.2.27) (RING finger protein 5) (Ram1 homolog) (HsRma1)
Gene: RNF5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981174
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4_3
Common GO terms	GO:0006511 - ubiquitin-dependent protein catabolic process GO:0036503 - ERAD pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1132 Hs			1 180
+	Hs
		803694 BAG6_HUMAN (1-1132): 0: 597: 100.00		TRI11_HUMAN (14-148): 2.69e-31: 119: 17.78
+	Hs
		584896 BAG6_HUMAN (1-1132): 0: 597: 100.00		RO52_HUMAN (23-148): 9.12e-25: 101: 18.11
+	Xl
		1140127 Q6DCM1_XENLA (16-542): 1.32e-26: 118: 13.37		Q5XGX4_XENLA (2-179): 3.83e-56: 176: 56.74
+	Xl
		1140144 Q801P8_XENLA (2-494): 1.16e-24: 112: 13.79		Q5XGX4_XENLA (2-179): 3.83e-56: 176: 56.74
+	Xl
		1140130 Q6GMC1_XENLA (17-87): 2.18e-27: 111: 34.72		Q5XGX4_XENLA (2-179): 3.83e-56: 176: 56.74
+	Xl
		1140133 Q6GQF3_XENLA (17-87): 9.53e-28: 111: 34.72		Q5XGX4_XENLA (2-179): 3.83e-56: 176: 56.74
+	Hs
		1292361 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		RN185_HUMAN (17-179): 7.02e-52: 166: 60.98
+	Hs
		1292358 UBQL4_HUMAN (6-549): 7.75e-26: 115: 11.19		RN185_HUMAN (17-179): 7.02e-52: 166: 60.98
+	Hs
		1292364 UBQL1_HUMAN (15-521): 2.36e-25: 114: 12.84		RN185_HUMAN (17-179): 7.02e-52: 166: 60.98
+	Hs
		924117 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		RN185_HUMAN (17-179): 7.02e-52: 166: 60.98
+	Hs
		749275 SC24C_HUMAN (380-696): 1.27e-39: 162: 24.18		BRCA1_HUMAN (25-76): 3.12e-19: 86.4: 34.62
+	Hs
		1318731 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		TRIM4_HUMAN (17-170): 3e-32: 122: 17.31
+	At
		1352316 DSK2A_ARATH (2-480): 1.97e-32: 135: 15.56		PEX10_ARATH (1-80): 5.99e-25: 100: 30.00
+	At
		1352315 DSK2B_ARATH (2-472): 1.45e-30: 130: 15.63		PEX10_ARATH (1-80): 5.99e-25: 100: 30.00
+	Hs
		1019380 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		TRI26_HUMAN (14-123): 1.73e-28: 112: 21.85
+	Hs
		1295780 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		RN170_HUMAN (12-133): 1.15e-26: 103: 22.48
+	Hs
		924151 RS27A_HUMAN (17-87): 2.18e-27: 111: 34.72		TRI31_HUMAN (19-126): 9.14e-27: 106: 20.91
+	Hs
		924402 RL40_HUMAN (17-87): 9.53e-28: 111: 34.72		TRI31_HUMAN (19-126): 9.14e-27: 106: 20.91
+	Mm
		924236 RS27A_MOUSE (17-87): 2.18e-27: 111: 34.72		RO52_MOUSE (10-156): 5.16e-24: 99.4: 13.51
+	Mm
		924253 RL40_MOUSE (17-87): 9.53e-28: 111: 34.72		RO52_MOUSE (10-156): 5.16e-24: 99.4: 13.51