HitPredict

Interactor 1: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Interactor 2: AMFR (Q9UKV5)
E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING finger protein 45) (gp78)
Gene: AMFR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.947

The method score is based on:

Property Details
Experiments 21636303, 23246001, 24424410, 26424800, 27387505, 32614325
Identification Methods affinity chromatography technology, x-ray crystallography, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CUE~ubiquitin, ubiquitin~zf-RING_2
Common GO terms GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016020 - membrane
GO:0036503 - ERAD pathway
GO:1990381 - ubiquitin-specific protease binding
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1132
Hs

1 643
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024