HitPredict

Interactor 1: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Interactor 2: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.755

The method score is based on:

Property Details
Experiments 8051214, 20562859
Identification Methods pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~CDC48_2, AAA~CDC48_N, AAA_lid_3~AAA_lid_3, AAA_lid_3~CDC48_2, AAA_lid_3~CDC48_N, CDC48_2~CDC48_2, CDC48_2~CDC48_N, CDC48_N~CDC48_N
Common GO terms GO:0000149 - SNARE binding
GO:0001921 - positive regulation of receptor recycling
GO:0005524 - ATP binding
GO:0005765 - lysosomal membrane
GO:0005794 - Golgi apparatus
and 23 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 744
Hs

1 744
+ Cg
+ At
+ Dm
+ Dm
+ Dm
+ Ce
+ Sp
+ Sc
+ Sc
+ Sc
+ Hs
+ Sc
+ Dm
+ Ce
+ Rn
+ Hs
+ Mm
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024