HitPredict

Interactor 1: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport GO:0019901 - protein kinase binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 744 Hs			1 196
+	Hs
		803890 NSF_HUMAN (1-744): 0: 572: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		436194 NSF_HUMAN (1-744): 0: 572: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		803895 NSF_HUMAN (1-744): 0: 572: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		803886 NSF_HUMAN (1-744): 0: 572: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564445 NSF_HUMAN (1-744): 0: 572: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		874798 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Sp
		963940 CDC48_SCHPO (99-500): 1.63e-71: 251: 28.11		CDC42_SCHPO (1-196): 2.54e-76: 228: 50.51
+	Hs
		874762 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		874786 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		545289 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436226 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		874748 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		874753 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		120367 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		177475 NVL_HUMAN (441-736): 2.24e-49: 188: 17.32		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67