HitPredict

Interactor 1: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 744 Hs			1 768
+	Hs
		1042056 AFG2A_HUMAN (31-459): 4.45e-75: 262: 24.72		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		874907 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		177499 NVL_HUMAN (441-736): 2.24e-49: 188: 17.32		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		874908 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		874909 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		874905 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Dm
		1097193 TERA_DROME (146-520): 1.06e-71: 251: 28.19		CUL1_DROME (29-768): 0: 669: 27.49
+	Hs
		874906 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		875192 TERA_HUMAN (146-479): 5.59e-69: 244: 31.05		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Sc
		636771 CDC48_YEAST (8-550): 3.28e-72: 253: 21.83		CDC53_YEAST (30-768): 0: 573: 22.08