HitPredict

Interactor 1: CIC1 (P38779)
Proteasome-interacting protein CIC1 (Core interacting component 1)
Gene: CIC1

Interactor 2: IF6 (Q12522)
Eukaryotic translation initiation factor 6 (eIF-6)
Gene: TIF6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 16429126, 16095611, 37968396
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0030687 - preribosome, large subunit precursor
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 376
Sc

1 245
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025